Schistocytes (helmet cells)


Schistocytes are erythrocyte fragments which are formed by mechanical action in small, damaged vessels, or by artificial cardiac valves. They are of variable shapes, typically however, half-moon or dough nut-shaped.


Schistocytes are, if not otherwise explicable (artificial cardiac valves and March hemoglobinuria), an alarming abnormality. They can be found in the following states with microangiopathic hemolytic anemia (MAHA):