Pappenheimer bodies and siderocytes


Pappenheimer bodies are fine-grained inclusions which are visible with Wright staining. Their iron content (hemosiderin) can be detected with iron staining. Erythrocytes with these types of inclusions are called siderocytes.


Siderocytes are an indication of an iron utilization disorder. They occur with sideroblastic anemia, thalassemia, after splenectomy and in lead intoxication.