Plasma cells

Plasma cells are encountered in bone marrow more often than in the peripheral blood. They constitute about of nucleated bone marrow cells (myelogram). However, they should not constitute more than 3% of bone marrow cells. Their main function is to produce immunoglobulins for the antibody-defense against infection.



Plasma cells have a coarse, round, eccentric nucleus and basophilic cytoplasm. A perinuclear halo (corresponding to the Golgi apparatus) can usually be identified. Inclusions may be present as well.